This is a report of an unusual mesodermal tumor present on the neck of a 65-year-old male Negro. The lesion was 1.5 cm high, skin colored, solid, cylindrically shaped and firmly bound to the underlying structures. On histochemical analysis there were three outstanding features namely (a) hyaline material, (b) an intense net of reticulum fibers, and (c) xanthoma cells. The hyaline material, which represented the bulk of the tumor, was strongly PAS positive, diastase resistant, and stained blue with Mallory's trichrome, thus suggesting the presence of collagen with an unusual increase in bound-carbohydrates. We are proposing to designate this tumor as a hyaline reticuloxanthoma.
Fleischmajer R, Shapiro L. Hyaline Reticuloxanthoma: A New Mesodermal Tumor. Arch Dermatol. 1969;99(4):434–440. doi:10.1001/archderm.1969.01610220062011
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