Presented by Rudolf L. Baer, MD.A 64-year-old white woman developed an erythematous scaly eruption on her nose and around her eyes in October 1967 which, over a period of two months, spread to her cheeks, neck, chest, thighs, and buttocks and which was associated with periorbital edema. There was no definite relationship to sunlight exposure, and she had no fever, arthritis, or muscle weakness at that time. She was hospitalized at Jackson Memorial Hospital, Miami, Fla, from Feb 12 to Feb 23, 1968. Clinical diagnoses at this time were lupus erythematosus (LE), possibly drug induced, or polymorphous light eruption. During that admission, all drugs that the patient had taken were withheld, eg, digoxin, thyroid, estrogenic substances conjugated (Premarin), furosemide (Lasix), polythiazide (Renese), chlordiazepoxide (Menrium), and tetracycline, with no improvement. Routine patch tests and photopatch tests to her cosmetics were negative. Minimal erythema threshold was normal. Pertinent laboratory studies
NEW YORK DERMATOLOGICAL SOCIETY. Arch Dermatol. 1969;99(5):629–634. doi:10.1001/archderm.1969.01610230121023
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