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May 1969

Progress in Allergy: Vol. 12

Arch Dermatol. 1969;99(5):645-646. doi:10.1001/archderm.1969.01610230137026

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The series Progress in Allergy furnishes up-to-date reviews of pertinent subjects by workers who have made significant contributions. "The present volume," writes editor Waksman in his Introduction, "illustrates three distinct facets of current immunologic research." Continuing, he enumerates these as auto-immunization, the central role of lymphocytes in immune responses, and a demonstration of the application of modern immunologic techniques to a clinical problem.

In their review of "The Action of Phytohemagglutinin In Vivo and In Vitro," Naspitz and Richter bring together the observations from their own work and those of 435 references to examine every aspect of phytohemagglutinin (PHA), including its preparation, purification, in vitro properties, cellular localization, and the morphologic and metabolic changes it can induce. They assess its in vitro action on cells from various disease and physiologic states, as well as its in vivo use in the human. They point out its use as a tool to

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