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June 1969

Sarcoid Granuloma in Secondary Syphilis

Arch Dermatol. 1969;99(6):748-752. doi:10.1001/archderm.1969.01610240106019

An unusual case of granulomatous secondary syphilis is presented. The infrequent occurrence of such a reaction in secondary syphilis is noted. Histological examination revealed a sarcoid granuloma. This pattern is characteristic of the allergic type of granuloma and suggests that the lesions in this patient represent a specific hypersensitivity reaction to the syphilitic infection.