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August 1969

Small-Intestinal Mucosa in Pemphigoid and Subcorneal Pustular Dermatosis

Author Affiliations

Newcastle upon Tyne, England

From the University Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, England.

Arch Dermatol. 1969;100(2):136-140. doi:10.1001/archderm.1969.01610260012002

The jejunal mucosa has been biopsied in ten patients with pemphigoid and in two patients with subcorneal pustular dermatosis. In none of these patients have the changes of the coeliac syndrome so common in patients with dermatitis herpetiformis been found. The practical importance of our observations is that if a severe jejunal mucosal abnormality is found in a patient thought to be suffering from pemphigoid that diagnosis should be reconsidered, as the coeliac syndrome has not yet been reported in this disease. No serious abnormality of the jejunal mucosa has so far been seen in subcorneal pustular dermatosis but the numbers studied are still very small.

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