A 45-year-old Korean man with lichen simplex chronicus on the scrotal skin was treated by overdosage of grenz radiation three years ago. A persistent, erythematopurpuric lesion with telangiectasia insidiously developed on the irradiated, hypermelanotic area six months after the final irradiation. A dark-reddish, sessile tumor appeared and gradually increased in size in the past three months. This was followed by the occurrence of three other similar tubers. Histologic findings of the tumors revealed those of angiokeratoma with acantholysis. It is an additional sequela of grenz radiation and also a warning to the unwary on the grenz-rays treatment.
Abe Y, Sugai T, Saito T. Radiation Angiokeratoma Following Grenz Radiation. Arch Dermatol. 1969;100(3):294–296. doi:10.1001/archderm.1969.01610270036008