Both occlusive tape alone and steroid incorporated into an occlusive tape will cause inhibition of enzyme activities in the lesions of psoriasis as well as in the normal-appearing skin. The steroid tape is more effective than the tape alone in producing these effects.
Halprin KM, Fukui K, Ohkawara A. Flurandrenolone (Cordran) Tape and Carbohydrate Metabolizing Enzymes: Use in the Epidermis of People With Psoriasis. Arch Dermatol. 1969;100(3):336–341. doi:10.1001/archderm.1969.01610270078018
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