Hyperkeratosis lenticularis perstans was first described by Flegel1 in 1958. We describe here the clinical and histological features of two female patients with widespread keratoses affecting the limbs, features which closely resemble those of the patient reported by Flegel. Cases of this condition have been reported by other authors (Gruneberg2; Donald and Hunter3; Kocsard et al4; and Hunter and Donald5. We consider this dermatosis deserves wider recognition on account of its characteristic features. The differential diagnosis of the condition is discussed in respect of the histological features in particular; the differences between it, Kyrle's disease, and stucco-keratoses of the extremities are tabulated.
Raffle EJ, Rogers J. Hyperkeratosis Lenticularis Perstans. Arch Dermatol. 1969;100(4):423–428. doi:10.1001/archderm.1969.01610280041005
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