Eccrine anhidrosis was produced using occlusive techniques with porous and nonporous tapes. The degree of sweat inhibition was measured and the more occlusive tapes produced the most marked anhidrosis. Plastic occlusive film (Saran Wrap) produced nearly as much anhidrosis as the most adherent and occlusive tape. It took between 14 to 23 days for the test site to recover from the experimentally produced anhidrosis.
The occlusion anhidrosis could not be appreciably altered by stripping the epidermis to glistening. This stripping should remove any overhydrated cells at the sweat pore ostia that could produce mechanical blockage.
The hypothesis is submitted that occlusion anhidrosis produces an effect on the eccrine duct or secretory coil and possibly a feedback mechanism which shuts off the sweat gland itself.
Gordon BI, Maibach HI. Adhesive Tape Anhidrosis. Arch Dermatol. 1969;100(4):429–431. doi:10.1001/archderm.1969.01610280047006
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