A 46-year-old nonalcoholic man with severe psoriasis developed cirrhosis following 63 months of methotrexate therapy. Four similar cases have been reported.
Epstein EH, Croft JD. Cirrhosis Following Methotrexate Administration for Psoriasis. Arch Dermatol. 1969;100(5):531–534. doi:10.1001/archderm.1969.01610290015003
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