Two patients with typical features of both ichthyosis linearis circumflexa and Netherton's syndrome are reported. Although these two rare variants of ichthyosis have previously been considered to be distinct, they actually appear to be the same entity manifesting as a peculiar defect in keratinization affecting the skin and hair.
The term "psoriasiform ichthyosis" is proposed to include ichthyosis linearis circumflexa-Netherton's syndrome, and perhaps other variants of ichthyosis with psoriasiform features which do not appear to fit into the existing classification of ichthyosiform dermatoses.
Altman J, Stroud J. Netherton's Syndrome and Ichthyosis Linearis CircumflexaPsoriasiform Ichthosis. Arch Dermatol. 1969;100(5):550–558. doi:10.1001/archderm.1969.01610290034007
* * SCHEDULED MAINTENANCE * *
The JAMA Network Sites will be conducting routine maintenance from 10/20/2017 through 10/21/2017. During this window access to content and authentication may be intermittently available. The JAMA Store will be completely unavailable during the maintenance window.