A 3-year-old girl with the Hand-Schüller-Christian type of histiocytosis-X had involvement of the nails and paronychium. These lesions responded to antineoplastic therapy and have recurred several times when such therapy was discontinued.
Kahn G. Nail Involvement in Histiocytosis-X. Arch Dermatol. 1969;100(6):699–701. doi:10.1001/archderm.1969.01610300049007
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