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December 1969

Ampicillin Sensitivity in Infectious Mononucleosis

Author Affiliations


From the departments of dermatology (Dr. Coskey) and medicine (Dr. Paul) of Wayne State University School of Medicine and Detroit General Hospital.

Arch Dermatol. 1969;100(6):717-719. doi:10.1001/archderm.1969.01610300067010

A patient with infectious mononucleosis developed a generalized maculopapular eruption after taking ampicillin trihydrate by mouth for eight days. This type of eruption occurs in most patients with infectious mononucleosis who are treated with ampicillin. Thus if a patient suspected of having infectious mononucleosis needs antibiotic therapy, ampicillin should be avoided.