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March 1970

Localized Epidermolytic Hyperkeratosis: A Form of Keratoderma of the Palms and Soles

Author Affiliations

New Haven, Conn; Miami, Fla

From the Section of Dermatology, Yale University School of Medicine, New Haven, Conn (Dr. Klaus), and the Department of Dermatology, University of Miami School of Medicine, Miami, Fla (Drs. Frost and Weinstein).

Arch Dermatol. 1970;101(3):272-275. doi:10.1001/archderm.1970.04000030016003

Nine patients with a familial type of diffuse hyperkeratosis of the palms and soles are reported. Skin biopsies (and, in one case, epidermal kinetic studies) showed the changes of epidermolytic hyperkeratosis. It is suggested that the category of epidermolytic hyperkeratosis be expanded to include this variety of keratoderma palmaris et plantaris.

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