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March 1970

Location of Proliferating Cells in Human Epidermis

Author Affiliations

Miami, Fla

From the Department of Dermatology, University of Miami School of Medicine, Miami, Fla.

Arch Dermatol. 1970;101(3):323-327. doi:10.1001/archderm.1970.04000030067010

The location of the proliferative pool of cells in normal epidermis, ichthyosis vulgaris, lamellar ichthyosis, X-linked ichthyosis, epidermolytic hyperkeratosis, and psoriasis was examined using autoradiographic and projection techniques.

A significant number of thymidine-labeled cells (deoxyribonucleic acid-synthesizing cells) were found above the basal cell layer in all conditions examined. Cell proliferation in the epidermis is not limited to the basal layer but also occurs in more superficial cells.

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