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April 1970

Basal Cell Epithelioma in Smallpox Vaccination Scar: Report of a Case

Author Affiliations

Charleston, SC

From the Department of Dermatology, Medical University of South Carolina, Charleston.

Arch Dermatol. 1970;101(4):416-417. doi:10.1001/archderm.1970.04000040038008

To my knowledge, only 45 cases of carcinoma appearing in smallpox vaccinations are in the literature. Basal cell carcinoma appeared in a smallpox scar 50 years after vaccination in a 64-year-old man. Significant evaluation of their relationship at this time is impossible. Whether this is a casual occurrence or a definite sequela to smallpox vaccination cannot be determined from present knowledge.

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