[Skip to Content]
[Skip to Content Landing]
May 1970

Histology of Autosomal Dominant Ichthyosis Vulgaris and X-linked Ichthyosis

Author Affiliations

Tel-Aviv, Israel

From the Department of Dermatology, Tel-Aviv University Medical School, Tel-Hashomer Government Hospital, Israel. Dr. Ackerman is currently at the Department of Dermatology, University of Miami School of Medicine, Miami, Fla.

Arch Dermatol. 1970;101(5):524-527. doi:10.1001/archderm.1970.04000050028004

The histology of autosomal dominant ichthyosis vulgaris and X-linked ichthyosis was studied using biopsy material from the arm and leg. Their characteristic histology is best demonstrated in the thick scales of the leg. Biopsy specimens from the arm, especially from the delicate scales of autosomal dominant ichthyosis vulgaris, may be similar microscopically to normal skin. Autosomal dominant ichthyosis vulgaris and X-linked ichthyosis are most readily distinguished histologically when specimens are obtained from regions of maximal scaling.