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September 1970

Society Transactions

Arch Dermatol. 1970;102(3):340-347. doi:10.1001/archderm.1970.04000090102019


Hypergammaglobulinemic Purpura, Acquired Ichthyosis, and Renal Tubular Acidosis. Presented by the Baylor College of Medicine Resident Staff.  This 41-year-old white man has an eight-year history of nephrocalcinosis secondary to renal tubular acidosis. In 1967, he was found to have hypergammaglobulinemia with purpura of the legs. There is a six-year history of a scaling eruption of the forearms and legs.Examination revealed multiple purpuric lesions on the extensor surfaces of the legs and feet. Also, a hyperpigmented scaly ichthyotic eruption involved the entire circumference of both legs and the extensor aspect of both forearms.Results of a routine complete blood cell count (CBC) were within normal limits. Total serum protein was 8.8 gm/100 cc, of which 3.7 gm/100 cc was albumin and 3.3 gm/100 cc was γ-globulin. Serum immunoglobulins were as follows: IgG, 3,340 mg/100 cc (normal 700 to 1,500); IgA, 340 mg/100 cc (normal

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