Characteristic suprabasal intraepithelial bullae with typical acantholytic cells were present in a biopsy specimen from an erosive lesion of the cervical esophagus. The patient's serum was positive for pemphigus intercellular antibodies. Contrary to present concepts, pemphigus vulgaris may extend to the esophagus. Although pemphigus of the esophagus is unusual, it should be considered and investigated in patients with pemphigus who have symptoms suggestive of esophageal involvement.
Raque CJ, Stein KM, Samitz MH. Pemphigus Vulgaris Involving the Esophagus. Arch Dermatol. 1970;102(4):371–373. doi:10.1001/archderm.1970.04000100019005
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: