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January 1971

Epidermolysis Bullosa Acquisita: Report of Three Cases and Review of All Published Cases

Author Affiliations


From the Department of Dermatology, Cleveland Clinic Foundation, Cleveland.

Arch Dermatol. 1971;103(1):1-10. doi:10.1001/archderm.1971.04000130003001

Epidermolysis bullosa acquisita (EBA) is a rare, nonhereditary, blistering disease with clinical features similar to epidermolysis bullosa dystrophica. The clinical features may often simulate porphyria cutanea tarda, pemphigus, or pemphigoid. Three new cases of EBA are discussed. The first patient had signs of a "lymphoma-like" disorder of lymph nodes. The other two patients had inflammatory disorders of the gastrointestinal tract. A review of all other reported cases of EBA shows a high incidence of associated systemic disease, amyloidosis, colitisenteritis, multiple myeloma, and diabetes mellitus.

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