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January 1971

Angiolymphoid Hyperplasia With Eosinophilia

Author Affiliations

Detroit; New York

From the departments of dermatology, Wayne State University School of Medicine and Detroit General Hospital, Detroit; (Dr. Mehregan); and the Department of Dermatology, College of Physicians and Surgeons, Columbia University, and the Dermatology Service, Presbyterian Hospital, New York (Dr. Shapiro).

Arch Dermatol. 1971;103(1):50-57. doi:10.1001/archderm.1971.04000130052007

Fourteen patients had solitary or multiple nodular lesions located within the dermis, and frequently the subcutis as well. The patients were mainly young females, with tumors ranging from 0.2 to 4 cm in diameter, localized mainly to the head. Histologically, the tumors showed the unusual combination of poorly differentiated proliferating vessels, tissue eosinophilia, and, at times, lymphoid follicle formation or arteritis or both. The lesions were apparently benign and can uaually be cured by excision. The term "angiolymphoid hyperplasia with eosinophilia" (ALH) describes the essential histopathologic features.