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January 1971

Pharmacological Treatment in Organ and Tissue Transplantation

Author Affiliations

Rochester, Minn

Arch Dermatol. 1971;103(1):114. doi:10.1001/archderm.1971.04000130116029

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This book is the published proceedings of an international symposium on the title subject. A total of 44 papers are presented under three headings. The first section on immunosuppressive chemotherapy is of value in providing a quick review of several of the drugs currently in clinical use or under investigation. It includes studies involving kidney, heart, lung, and bone marrow transplants.

The second section dealing with "antireactional" therapy is comprised in large part with the use of agents not generally considered immunosuppressive, in modifying the immune response. Enzymes, antienzymes, indomethacin, histamine, and heparin were some of the agents used.

The final section is concerned with evaluation of antilymphocytic serum (ALS) and methods for lymphatic ablation. It presents a cross section of current studies as to mode of action, clinical effectiveness, and means of preparation and assay of ALS.

Taken as a whole the book gives a rather spotty bird's eye

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