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February 1971

Isozymes of NADP-linked Isocitric Dehydrogenase in Psoriasis and Human Basal Cell Carcinoma

Author Affiliations

Miami, Fla

From the Dermatology Service, Veterans Administration Hospital, and the Department of Dermatology, University of Miami School of Medicine, Miami, Fla. Drs. Fukui and Ohkawara are now at the University of Hokkaido Medical School, Sapporo, Hokkaido, Japan.

Arch Dermatol. 1971;103(2):185-190. doi:10.1001/archderm.1971.04000140071012

Four isozymes of nicotinamide-adenine dinucleotide phosphate (NADP) linked isocitric dehydrogenase can be demonstrated by starch gel electrophoresis in normal human epidermis. In the lesions of psoriasis and in basal cell carcinoma only two of these isozymes can be demonstrated. With healing of the psoriatic lesion the two missing isozymes return.