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February 1971

1-Chloro-2,4-Dinitrobenzene as an Algicide: Report of Four Cases of Contact Dermatitis

Author Affiliations

Palo Alto, Calif; Whittier, Calif; Sunnyvale, Calif

From the Palo Alto (Calif) Medical Clinic (Dr. Adams); Department of Medicine, University of Southern California, Los Angeles (Dr. Zimmerman) and the Lockheed Missiles and Space Co., Sunnyvale, Calif (Drs. Bartlett and Preston).

Arch Dermatol. 1971;103(2):191-193. doi:10.1001/archderm.1971.04000140077013

After many years of limitation to experimental studies of contact allergic sensitization, 1-chloro-2,4-dinitrobenzene (2,4-dinitro-1-chlorobenzene) has again appeared in the occupational environment as an algicide for cooling water. Four cases of contact dermatitis in air-conditioning repairmen occurred, and a description of the case histories of three of them is given. The authors emphasize the necessity for engineering completely closed systems which afford no human contact with this highly allergenic substance.

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