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March 1971

Reevaluation of Ichthyosis and Hair Shaft Abnormalities

Author Affiliations

New Haven, Conn

From the Section of Dermatology, Department of Medicine, Yale-New Haven Medical Center, New Haven, Conn.

Arch Dermatol. 1971;103(3):266-271. doi:10.1001/archderm.1971.04000150036005

Trichorrhexis invaginata associated with ichthyosis linearis circumflexa occured in a 36-year-old man. Other similar reports are reviewed, and it is suggested that the original patient reported by Netherton probably had a combination of lamellar ichthyosis and trichorrhexis invaginata. Other combinations of hair shaft abnormalities with ichthyosis should not be designated as Netherton's syndrome until the relationship between ichthyosis linearis circumflexa and lamellar ichthyosis is established.

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