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April 1971

Dermatologic Manifestations of Fatal Granulomatous Disease of Childhood

Author Affiliations

Chicago; Minneapolis

From the Section of Dermatology, the Pritzker School of Medicine, University of Chicago (Dr. Windhorst); and the Department of Pathology, University of Minnesota, Minneapolis (Dr. Good).

Arch Dermatol. 1971;103(4):351-357. doi:10.1001/archderm.1971.04000160001001

The cutaneous lesions of the hereditary defect in phagocyte function, chronic granulomatous disease of childhood, are illustrated. Skin lesions are an early manifestation of this syndrome and prompt recognition may favorably influence the course of this serious condition, hence dermatologists should be familiar with the types of lesions presented and their complications. In addition, the nature of the lesions and the overall disease process illustrate the role that phagocytes may play in the cutaneous defense system.

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