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April 1971

Malignant Transformation in Giant Congenital Pigmented Nevus: Death in Early Childhood

Arch Dermatol. 1971;103(4):428-432. doi:10.1001/archderm.1971.04000160078012

Malignant melanoma developed at about the end of the first year of life in an infant boy. The tumor arose in a giant congenital pigmented nevus that had been treated with betamethasone valerate. Multiple metastases developed, and death supervened at the age of 28 months.