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May 1971

A New Approach to the Reduction of Sebum Secretion

Author Affiliations

Albuquerque, NM

From the departments of neurology and medicine, University of New Mexico School of Medicine, Albuquerque.

Arch Dermatol. 1971;103(5):492-493. doi:10.1001/archderm.1971.04000170026005

Sebum secretion was measured by a quantitative gravimetric method in nine patients with Parkinson's syndrome. The patients were tested before and at intervals after the administration of levodopa (L-DOPA). A striking reduction in sebum secretion occurred in four patients, and one had a less dramatic decrease. The results of this study suggest a new approach in the search for therapeutically useful agents for the treatment of seborrhea and acne.