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May 1971


Author Affiliations

Department of Dermatology Kyoto Prefectural University of Medicine Kawara-Machi, Hirokoji, Kamikyo-Ku Kyoto, Japan

Arch Dermatol. 1971;103(5):564-565. doi:10.1001/archderm.1971.04000170098027

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To the Editor.—  Dr. Chernosky and his associates (Arch Derm96:611-624, 1967, and 99:401-407, 1969) stressed the importance of sunlight in the pathogenesis of disseminated superficial actinic porokeratosis (DSAP) and succeeded in the formation of a new lesion of porokeratosis when the periphery of a lesion was autotransplanted. The assumption that porokeratosis of Mibelli is benign heritable derangement of the metabolism of some epidermal cells was made by Dr. Pinkus (Arch Derm102:235-236, 1970).In Japan as many as 359 patients with porokeratosis of Mibelli or DSAP were reported since 1904. Of these there were only 35 reports that referred to tuberculin test (Pirquet's or Mantoux's reaction) (Table). A negative reaction was described in 29 cases and a weakly positive reaction in one case. Eighty-seven percent (30 of 35) of the patients tested had depressed tuberculin skin reactivity.The depression of tuberculin sensitivity has been shown not only

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