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June 1971


Author Affiliations

Departments of Dermatology and Haematology North Staffordshire Hospital Centre Stoke-on-Trent England

Arch Dermatol. 1971;103(6):678-679. doi:10.1001/archderm.1971.04000180104016

To the Editor.—  In the August 1970 issue of the Archives (102:151-153), Preger et al reported the lack of functional or structural evidence of enteropathy (malabsorption) in eight patients with psoriasis. This report contrasts sharply with the findings of Shuster et al, 1967,1 and our own, hitherto unpublished, findings.Fifty-two patients admitted to the North Staffordshire Hospital Centre, Stoke-on-Trent, England, suffering from eczema or psoriasis have been observed for evidence of folic acid malabsorption; 49 of these patients have been screened for the presence of steatorrhea. Folic acid absorption was measured in all cases by using Lactobacillus casei as the test organism (Kelly and Davies, 19632; Giles, 19663; Hepner et al, 19684). By this method, a rise in the serum folate level of less than 80 ng/ml after an oral loading dose of 40μ/kg was considered abnormal. In several patients, the conventional method of estimating

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