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July 1971

Allergic Contact Dermatitis From Ragweeds (Ambrosia Species): The Role of Sesquiterpene Lactones

Author Affiliations

Vancouver, British Columbia; Regina, Saskatchewan; Vancouver, British Columbia

From the Division of Dermatology (Dr. Mitchell) and the Department of Botany (Drs. Dupuis and Towers), University of British Columbia, Vancouver, and Medical Arts Clinic, Regina, Saskatchewan (Dr. Roy).

Arch Dermatol. 1971;104(1):73-76. doi:10.1001/archderm.1971.04000190075012

Allergic eczematous contact dermatitis caused by ragweeds (Ambrosia), named "ragweed oleoresin contact dermatitis," was found to be due to ten sesquiterpene lactones possessing a methylenegroup attached to the lactone. An additional 14 lactones possessing such a group and derived from ragweeds, are probably allergenic.

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