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October 1971

Topically Applied Tretinoin for Senile (Solar) Comedones

Author Affiliations


From the Department of Dermatology, University of Pennsylvania, School of Medicine, Philadelphia.

Arch Dermatol. 1971;104(4):420-421. doi:10.1001/archderm.1971.04000220078015

The daily topical application of 0.1% tretinoin (vitamin A acid) solution was very effective in eliminating senile comedones from the faces of four middle-aged men.