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January 1972

Juvenile Generalized Pustular Psoriasis: A Report of Five Cases and a Review of the Literature

Author Affiliations

Edinburgh; Carlisle, England

From the Skin Department, Royal Infirmary, Edinburgh (Drs. Khan and Peterkin), and the Cumberland Infirmary, Carlisle, England (Dr. Mitchell). Dr. Khan is now with Clayton Hospital, Wakefield, Yorkshire, England.

Arch Dermatol. 1972;105(1):67-72. doi:10.1001/archderm.1972.01620040039007

Five children developed generalized pustular psoriasis reported, and the cases of similar patients have previously been described in the literature. Various investigations provided no real clue to the etiology, but there was a relatively high incidence of seborrheic dermatitis. In contrast to adult patients, in only 12% was there a prior history of psoriasis vulgaris. The disease was generally milder than in the adult, and attacks remitted within some weeks on bland therapy in the hospital. In these patients systemic corticosteroid therapy is not to be recommended and may lead not only to prolongation and aggravation of the attacks, but also to complications, especially virus infections which may prove fatal.