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January 1972

Quaternary Ammonium Compound Contact Dermatitis From a Deodorant

Author Affiliations


From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia. Dr. Shmunes is now with the National Institute for Occupational Safety and Health, Cincinnati.

Arch Dermatol. 1972;105(1):91-93. doi:10.1001/archderm.1972.01620040059014

During the last decade, the diverse use of quaternary ammonium compounds has greatly increased. Though quaternary ammonium compounds have been generally considered an unlikely allergen in the development of contact dermatitis, they do have a potential to induce sensitivity, particularly in damaged skin. This report describes a patient with a history of persistent nummular eczema, who developed an axillary dermatitis which was traced to a quaternary ammonium compound contained in his roll-on deodorant.