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March 1972

Linear Porokeratosis of Mibelli

Arch Dermatol. 1972;105(3):426-429. doi:10.1001/archderm.1972.01620060064013

We have seen two cases of linear porokeratosis. Observations have been made on different forms of therapy and possible pathogenesis. Linear porokeratosis of Mibelli would seem to be best explained on the basis of an abnormal clone of cells carrying the "porokeratosis trait" distributed along a dermatome area early in embryogenesis. What factors may later activate the area to develop clinical lesions of linear porokeratosis are not known.