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June 1972

Allergic Reaction to Benzophenone: Simultaneous Occurrence of Urticarial and Contact Sensitivities

Author Affiliations

New York

From the Department of Dermatology, New York University School of Medicine.

Arch Dermatol. 1972;105(6):906-908. doi:10.1001/archderm.1972.01620090076017

A black man with a broad-spectrum light sensitivity simultaneously showed an urticarial and contact sensitivity to a preparation containing 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid (sulisobenzone). Both the benzophenone and sulfonic acid parts of the molecule were required for elicitation of the contact reaction, while benzophenone alone elicited the urticarial reaction.