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October 1972

Triamcinolone and Pyoderma Gangrenosum

Arch Dermatol. 1972;106(4):599-600. doi:10.1001/archderm.1972.01620130105039

To the Editor.—  We have treated a patient with pyoderma gangrenosum with intralesionally administered triamcinolone acetonide. The patient had such an immediate dramatic response and has been controlled with such low doses of corticoids that we propose this method as the treatment of choice when corticosteroids are required for therapy for this disease.

Report of a Case  In July 1971, a 71-year-old retired dentist noted "pimples" on his scrotum and was treated with antibiotics. Biopsy of the lesion on three separate occasions showed abscess formation and chronic nonspecific inflammatory reaction. Tissue cultures, smears, and special stains for fungi and acid-fast bacteria were negative. Because the scrotal lesion suddenly became extensive and two new lesions developed on his left arm, he was hospitalized in November. There was no history of trauma to the involved areas and he denied gastrointestinal or recent joint disorder symptoms. Past history included hospitalizations for congestive