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November 1972

Macular Amyloidosis

Author Affiliations

White Plains, NY

Arch Dermatol. 1972;106(5):766-767. doi:10.1001/archderm.1972.01620140100032

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To the Editor.—  Subsequent to the submission of an article on macular amyloidosis by Brownstein and Hashimoto1 to the Archives, a case was presented at each of two meetings of the Dermatologic Society of Greater New York (Oct 21, 1971 and Jan 20, 1972) that fit the description of the patients reported by Gibbs and Frank2 as "a peculiar spotty pigmentation." At these meetings, it was pointed out that the lesions presented resembled macular amyloidosis clinically, but neither of the patients had amyloid on histopathologic study. Dr. Gibbs, who was at the meetings, pointed out that of their four patients who had a biopsy performed, only one showed the presence of amyloid. Dr. Brownstein, at the Jan 20, 1972 meeting, confirmed that he also had seen cases such as those reported by Gibbs and Frank with lesions clinically indistinguishable from macular amyloidosis but in which amyloid could not

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