Two cases of fibromatosis are reported. The first was in a 5-year-old boy with a lesion in the abdominal wall present since birth. Histologic findings revealed a fibrocollagenous proliferative process affecting the lower two thirds of the dermis, subcutaneous tissue, and fascia. The second case was in a 15-year-old girl with an indurated plaque involving the thigh of two years' duration. Histologic findings revealed connective tissue proliferation involving the subcutaneous tissue and muscle. Perusal of the literature shows that certain fibromatoses with benign structure may have the potential to invade adjacent structures. A recurrence is almost predictable if these lesions are not completely removed.
Fleischmajer R, Nedwich A, Reeves JRT. Juvenile Fibromatoses. Arch Dermatol. 1973;107(4):574–579. doi:10.1001/archderm.1973.01620190050012
Customize your JAMA Network experience by selecting one or more topics from the list below.