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April 1973

Eczema Vaccinatum and Eczema Herpeticum in Darier Disease

Author Affiliations


From the Division of Dermatology (Drs. Carney and Pomeranz) and the Department of Pediatrics (Drs. Caroline and Nankervis), Cleveland Metropolitan General Hospital. Dr. Caroline is now at University Hospital, Case-Western Reserve University School of Medicine, Cleveland.

Arch Dermatol. 1973;107(4):613-614. doi:10.1001/archderm.1973.01620190085023

A patient with known Darier disease developed separate secondary viral infections due to vaccinia and herpes simplex viruses. The first infection with vaccinia virus occurred while the patient was pregnant. Vaccinia hyperimmune γ-globulin was used to treat the patient who made an uneventful recovery and delivered a healthy infant approximately seven months later.