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November 1973


Arch Dermatol. 1973;108(5):734-735. doi:10.1001/archderm.1973.01620260074037

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Amelanotic Melanoma vs Reticulohistiocytic Granuloma (Reticulohistiocytoma) vs Atypical Fibroxanthoma Possibly Undergoing Malignant Change. Presented by Samuel Ayres, Jr., MD, Richard Mihan, MD.  A 69-year-old white man had a tumor on his left cheek for about seven months. Initially, another dermatologist had performed a biopsy and had administered two x-ray treatments of 155 roentgens each without improvement. The lesion increased in size, and during the past few months indurative areas developed in the left preauricular and submandibular region.Examination revealed a large elevated, discrete nodule with a base of about 2.5 cm. The borders were round and the surface was composed of granulation tissue with slight discharge. An inflammatory halo surrounding the mass extended toward the large firm subcutaneous mass in front of the left ear. A smaller indurated area was present at the angle of the jaw.

Discussion  Dr. Joseph I. Mills: Purvis and Helwig in 1954 reviewed 44 cases

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