A 51-year-old man with idiopathic hypoparathyroidism that had been untreated for more than nine years developed erythematous lesions with erosion and lamellar scales resembling exfoliative dermatitis. Depilation of scalp and axillary hair, nail changes, and cataracts were also noted. These skin changes appeared almost simultaneously with severe reduction of the serum calcium level. Treatment with ergocalciferol and gluconate calcium greatly improved these dermal lesions as well as other hypocalcemic symptoms. Normalization of the serum calcium level followed.
It is likely that exfoliative dermatitis-like lesions may occur as skin manifestations of idiopathic hypoparathyroidism, although such manifestations are extremely rare.
Kyoko Hirano, Akira Ishibashi, Yoshikazu Yoshino. Cutaneous Manifestations in Idiopathic Hypoparathyroidism. Arch Dermatol. 1974;109(2):242–244. doi:10.1001/archderm.1974.01630020054014