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April 1974

Allergic Contact Dermatitis Due to Halotex Solution

Author Affiliations

Madison, Wis

Arch Dermatol. 1974;109(4):572. doi:10.1001/archderm.1974.01630040076027

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To the Editor.—  Halotex Solution and Halotex Cream, containing 1% haloprogin as the active ingredient, have recently been detailed as a new, effective treatment for superficial fungal infections of the skin. A patient who was being treated for chronic tinea cruris developed an allergic contact dermatitis due to Halotex Solution. Subsequent patch testing revealed that the patient was allergic to diethyl sebacate, a soubilizing agent found in both Halotex Solution and Halotex Cream.

Report of a Case  A 19-year-old white man with a chronic dermatitis in both groin areas was examined on Feb 12, 1973. A potassium hydroxide examination showed numerous mycelia, and a diagnosis of tinea cruris was made. Treatment was started using Halotex Solution applied locally twice daily and 500 mg/day of griseofulvin (microsize), administered orally with a fatty meal.On March 21, 1973, the patient returned with an acute dermatitis of six days' duration that was present

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