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June 1974

Flucytosine: An Effective Oral Treatment for Chromomycosis

Author Affiliations

Gainesville, Fla; Jacksonville, Fla; Winston-Salem, NC

From the Department of Medicine, University of Florida, College of Medicine, Gainesville (Drs. Mauceri, Cullen, and Johnson), and the Department of Medicine, University of Florida (Jacksonville Division), College of Medicine, Jacksonville, Fla (Dr. Vandevelde). Dr. Johnson is now at Bowman Gray School of Medicine, Winston-Salem, NC.

Arch Dermatol. 1974;109(6):873-876. doi:10.1001/archderm.1974.01630060051015

Orally administered flucytosine appeared to successfully eradicate chromomycosis in three patients. The duration of therapy should be adequate for complete clinical and mycological evidence of cure. Flucytosine is easily administered and the untoward effects are minor, infrequent, and easily reversible. Flucytosine appears to be a major improvement over prior therapy for this chronic and progressive disease.

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