A man developed allergic contact dermatitis in a split-thickness skin autograft. The year-old donor site flared spontaneously. This unusual finding could be due to nonspecific factors associated with injured skin; however, it is proposed that regional or permanently altered skin protein, common to both sites, contributed to it on an immunological basis.
William P. Jordan, James W. Finn. Flare DermatitisOccurrence in Skin Transplant Donor Site Following Sensitization in Recipient Site. Arch Dermatol. 1974;109(6):884–886. doi:10.1001/archderm.1974.01630060060017