A dense collection of mature plasma cells predominated in the biopsy specimen from a mass on the lower lip of a 67-year-old woman. Attempts to identify specific benign or malignant processes failed, attempts to induce plasma cell infiltrations on mucosal and nonmucosal surfaces by allergic and irritant stimuli were not successful. It is suggested that plasma cell cheilitis is not specific for any one disease process but may represent a component of the secretory immunologic response.
Richard D. Baughman, Peter Berger, Warren M. Pringle. Plasma Cell Cheilitis. Arch Dermatol. 1974;110(5):725–726. doi:10.1001/archderm.1974.01630110023003