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November 1974

Generalized Perforating Granuloma Annulare

Author Affiliations

Kaduna, Nigeria

Arch Dermatol. 1974;110(5):809. doi:10.1001/archderm.1974.01630110087031

To the Editor.—  The articles of Duncan et al1 and Izumi2 on generalized perforating granuloma annulare prompted us to report a case of ours.

Report of a Case.—  A 42-year-old woman was referred to the Department of Dermatology, Wroclaw School of Medicine, Poland in June 1971 for evaluation of gradually progressive papular lesions scattered over the extremities, trunk, and face. The asymptomatic skin lesions had been first noticed about one year ago. The family history was negative for skin diseases. The patient had a 15-year history of progressive neural atrophy. Physical examination revealed a diffuse eruption of more than 500 papules, involving most areas of skin, except for the palms, with maximum involvement of face, extensor aspects of extremities, interscapular region, soles, and pinnae of the ears. The majority of the lesions were 3 to 5 mm erythematous papules. Individual papules developed a central umbilication, then the center

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