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November 1974

Locally Applied Adrenocorticoids in Treatment of Herpes Simplex

Arch Dermatol. 1974;110(5):811. doi:10.1001/archderm.1974.01630110089034

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To the Editor.—  At a recent dermatologic conference at New York University Medical Center, during a discussion of therapy for recurrent herpes simplex of the lips, there was near unanimity regarding the contraindication of using topically applied adrenocorticoids locally on skin. The basis for such contraindication was information to be found in both the circular accompanying the topical adrenocorticoids and in the Physician's Desk Reference (PDR). No one could recount a dire consequence of the occasional use of the steroid, although one colleague claimed he had heard of a patient who developed fulminant herpes ophthalmicus following topical application of the steroid for herpes of the ipsilateral cheek. When the 1974 PDR was actually read, the following contraindications were found to be listed:Contraindicated in varicella and vaccinia: Cort Dome, Dermacort, Fluonid, Kenalog, Lidex, Meticorten, Synalar, Texacort, TridesilonContraindicated in viral diseases of the skin, such as varicella and vaccinia: Aristocort,

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