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November 1974

Intravascular Angiomatosis in Cutaneous Vessels-Reply

Arch Dermatol. 1974;110(5):812. doi:10.1001/archderm.1974.01630110090037

To the Editor.—  We are glad to learn that other pathologists have encountered this lesion and that some have also noted its capacity to simulate angiosarcoma on cytologic grounds. We certainly agree that angiosarcoma primarily located within large vascular spaces of the skin is one of the rarest neoplasms to be observed, if it exists at all. We also agree that the lesions we have reported are probably reactive in nature, as we have stated in our article.Drs. Salyer and Salyer strongly feel that these lesions represent peculiarly organizing thrombi. This is certainly possible, and we discussed this interpretation in our article. However, we also mentioned the weak points of this hypothesis, which led to the conclusion that the question of pathogenesis should be left open. We can only reiterate here that if the lesions we are describing are thrombi, they are thrombi of a most peculiar character.A

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