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November 1974


Arch Dermatol. 1974;110(5):817-821. doi:10.1001/archderm.1974.01630110091042

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Dimorphous Leprosy. Presented by Judith Schiffner, MD, and the Staff of the Department of Dermatology, University of Southern California School of Medicine.  A 53-year-old Filipino woman, resident in the United States for 1½ years, noticed an erythematous nodule on her left elbow and several smaller nodules on her face five months ago. She came to the Dermatology Clinic with a generalized eruption of one week's duration. Her only other complaint was nasal congestion.Physical examination showed indurated nodules and large, raised desquamating plaques on the face, trunk, and extremities. There was no loss of sensory perception. Fite stain of the biopsy specimen was negative, but immunofluorescent studies showed the presence of Mycobacterium leprae.The patient was admitted to the hospital on Dec 19, 1973. Her lesions became spontaneously dusky and less red after admission. On Dec 24, 1973, treatment was started with thalidomide, 100 mg given twice a day, but

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